Tell patients that hydrocodone bitartrate and acetaminophen tablets could bring about a uncommon but likely lifetime-threatening problem ensuing from concomitant administration of serotonergic drugs.

Tell female patients of reproductive potential that extended utilization of hydrocodone bitartrate and acetaminophen tablets throughout pregnancy may end up in neonatal opioid withdrawal syndrome, which may be lifestyle-threatening if not acknowledged and dealt with [see WARNINGS, Safeguards; Pregnancy].

The subcommittee also discovered 7 people that died from fentanyl overdoses immediately after sending cash and obtaining deals from among the list of six online sellers, and it observed eighteen those who were arrested for drug-relevant offenses soon after building purchases as a result of them. Listed here’s the way it describes a person of such deaths in its report:

Prolonged utilization of opioid analgesics in the course of pregnancy for medical or nonmedical purposes may result in Bodily dependence within the neonate and neonatal opioid withdrawal syndrome Soon immediately after beginning.

You might also be at risk for an opioid overdose when first starting off Vicodin or if your dose is greater. Naloxone is definitely an unexpected emergency therapy for an opioid overdose. Request your Health care provider or even a pharmacist about acquiring naloxone.

Follow people carefully for respiratory depression, Particularly throughout the to start with 24-72 hours of initiating therapy and adhering to dosage boosts with hydrocodone bitartrate and acetaminophen tablets and alter the dosage appropriately [see WARNINGS].

Particular Senses : Instances of Listening to impairment or long lasting reduction are already noted predominately in people with Continual overdose.

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Therapeutic doses of acetaminophen have negligible results on the cardiovascular or respiratory units; on the other hand, poisonous doses could trigger circulatory failure and immediate, shallow respiration.

Results over the liver warning: Vicodin consists of a combination of hydrocodone and acetaminophen. In bigger doses (normally much more than 4000 mg every day), acetaminophen can damage your liver and in many cases cause liver failure.

If the extent of discomfort raises after dosage stabilization, make an effort to identify the source of amplified ache just before increasing the hydrocodone bitartrate and acetaminophen tablets dosage.

Hydrocodone bitartrate and acetaminophen tablets should not be abruptly discontinued within a bodily dependent client [see DOSAGE AND ADMINISTRATION]. If hydrocodone bitartrate and acetaminophen tablets are abruptly discontinued in a physically dependent individual, a withdrawal syndrome may well manifest.

This doc doesn't incorporate all probable side effects and Many others might occur. Look at along with your medical professional For added information about Uncomfortable side effects.